Ontology highlight
ABSTRACT:
SUBMITTER: Balu B
PROVIDER: S-EPMC3811562 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Balu Bharath B Campbell Christopher C Sedillo Jennifer J Maher Steven S Singh Naresh N Thomas Phaedra P Zhang Min M Pance Alena A Otto Thomas D TD Rayner Julian C JC Adams John H JH
Eukaryotic cell 20130628 9
Intraerythrocytic development of the human malaria parasite Plasmodium falciparum appears as a continuous flow through growth and proliferation. To develop a greater understanding of the critical regulatory events, we utilized piggyBac insertional mutagenesis to randomly disrupt genes. Screening a collection of piggyBac mutants for slow growth, we isolated the attenuated parasite C9, which carried a single insertion disrupting the open reading frame (ORF) of PF3D7_1305500. This gene encodes a pr ...[more]