Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Torralba M
PROVIDER: S-EPMC3817505 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Pérez-Torralba Marta M Claramunt Rosa M RM Angeles García M M López Concepción C Torralba M Carmen MC Rosario Torres M M Alkorta Ibon I Elguero José J
Beilstein journal of organic chemistry 20131021
Two novel tetrafluorinated 1,5-benzodiazepinones were synthesized and their X-ray structures determined. 6,7,8,9-Tetrafluoro-4-methyl-1,3-dihydro-2H-1,5-benzodiazepin-2-one crystallizes in the monoclinic P21/c space group and 6,7,8,9-tetrafluoro-1,4-dimethyl-1,3-dihydro-2H-1,5-benzodiazepin-2-one in the triclinic P-1 space group. Density functional theory studies at the B3LYP/6-311++G(d,p) level were carried out on these compounds and on four non-fluorinated derivatives, allowing to calculate ge ...[more]