Ontology highlight
ABSTRACT:
SUBMITTER: Isaacman MJ
PROVIDER: S-EPMC3817994 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Biomacromolecules 20130821 9
The strain-promoted azide-alkyne cycloaddition represents an optimal metal-free method for the modular coupling of amphiphilic polymer blocks. Hydrophilic poly(oxazoline) (PMOXA) or poly(ethylene glycol) (PEG) A-blocks were coupled with a hydrophobic poly(siloxane) B-block to provide triblock copolymers capable of self-assembling into vesicular nanostructures. Stealth properties investigated via a complement activation assay revealed the superior in vitro stealth attributes of polymeric vesicles ...[more]