Ontology highlight
ABSTRACT:
SUBMITTER: Kasinath V
PROVIDER: S-EPMC3821934 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20130925 40
Conformational entropy is a potentially important thermodynamic parameter contributing to protein function. Quantitative measures of conformational entropy are necessary for an understanding of its role but have been difficult to obtain. An empirical method that utilizes changes in conformational dynamics as a proxy for changes in conformational entropy has recently been introduced. Here we probe the microscopic origins of the link between conformational dynamics and conformational entropy using ...[more]