Ontology highlight
ABSTRACT:
SUBMITTER: Andermann ML
PROVIDER: S-EPMC3840091 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Andermann Mark L ML Gilfoy Nathan B NB Goldey Glenn J GJ Sachdev Robert N S RN Wölfel Markus M McCormick David A DA Reid R Clay RC Levene Michael J MJ
Neuron 20131017 4
Two-photon imaging of cortical neurons in vivo has provided unique insights into the structure, function, and plasticity of cortical networks, but this method does not currently allow simultaneous imaging of neurons in the superficial and deepest cortical layers. Here, we describe a simple modification that enables simultaneous, long-term imaging of all cortical layers. Using a chronically implanted glass microprism in barrel cortex, we could image the same fluorescently labeled deep-layer pyram ...[more]