Ontology highlight
ABSTRACT:
SUBMITTER: Qian Y
PROVIDER: S-EPMC3848839 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Qian Yun Y Liu Sijun S Lu Feng F Li Huizhang H Dong Meihua M Lin Yudi Y Du Jiangbo J Lin Yuan Y Gong Jianhang J Jin Guangfu G Dai Juncheng J Hu Zhibin Z Shen Hongbing H
BMC genetics 20130922
<h4>Background</h4>Genome-wide association study (GWAS) has identified that rs8050136 C/A polymorphism in fat mass and obesity-associated gene (FTO) was associated with the risk of type 2 diabetes (T2D) in Europeans. But this association was abolished after adjustment for body mass index (BMI), suggesting that the effect of rs8050136 on T2D risk might be mediated by BMI in Europeans. However, the findings in subsequent studies were inconsistent among Asian populations. To determine whether rs805 ...[more]