Ontology highlight
ABSTRACT:
SUBMITTER: Bueno-Silva B
PROVIDER: S-EPMC3855307 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Bueno-Silva B B Koo H H Falsetta M L ML Alencar S M SM Ikegaki M M Rosalen P L PL
Biofouling 20131007 10
The present study examined the influences of the neovestitol-vestitol (NV) containing fraction isolated from Brazilian red propolis on the development of biofilm and expression of virulence factors by Streptococcus mutans using saliva-coated surfaces of hydroxyapatite. In addition, NV was tested in a rodent model of dental caries to assess its potential effectiveness in vivo. Topical applications of NV (800 μg ml(-1)) significantly impaired the accumulation of biofilms of S. mutans by largely di ...[more]