CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents.
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ABSTRACT:
SUBMITTER: Dorazio SJ
PROVIDER: S-EPMC3857136 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
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CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents.
Dorazio Sarina J SJ Olatunde Abiola O AO Spernyak Joseph A JA Morrow Janet R JR
Chemical communications (Cambridge, England) 20131101 85
The first examples of air-stable Co(II) paraCEST MRI contrast agents are reported. Amide NH protons on the complexes give rise to CEST peaks that are shifted up to 112 ppm from the bulk water resonance. One complex has multiple CEST peaks that may be useful for ratiometric mapping of pH. ...[more]
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