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A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores.

ABSTRACT: Common ground: copper-catalyzed coupling reactions can be used for the high-yielding preparation of widely used oxazine and xanthene fluorophores from a common diaryl ether intermediate on a gram-scale. This general approach may facilitate the future development of novel fluorophores and probes with unique properties.

SUBMITTER: Anzalone AV

PROVIDER: S-EPMC3860831 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores.

Anzalone Andrew V AV Wang Tracy Y TY Chen Zhixing Z Cornish Virginia W VW

Angewandte Chemie (International ed. in English) 20121121 2

Common ground: copper-catalyzed coupling reactions can be used for the high-yielding preparation of widely used oxazine and xanthene fluorophores from a common diaryl ether intermediate on a gram-scale. This general approach may facilitate the future development of novel fluorophores and probes with unique properties. ...[more]

PMID: 23169599

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