Ontology highlight
ABSTRACT:
SUBMITTER: Bella M
PROVIDER: S-EPMC3869217 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20131127
The synthesis of 5,6- and 7,8-diaminoquinoline derivatives starting from angularly annelated selenadiazoloquinolones is presented. Simple chlorination of the pyridone ring followed by reductive deselenation of the 1,2,5-selenadiazole ring afforded novel 4-chloro-o-diaminoquinolines. Dechlorination of 4-chloro-7,8-diaminoquinoline gave 7,8-diaminoquinoline hydrochloride which was successfully employed as starting material in the synthesis of condensed nitrogen heterocycles. ...[more]