Osteophilic multilayer coatings for accelerated bone tissue growth.
Ontology highlight
ABSTRACT:
SUBMITTER: Shah NJ
PROVIDER: S-EPMC3870474 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Osteophilic multilayer coatings for accelerated bone tissue growth.
Shah Nisarg J NJ Hong Jinkee J Hyder Md Nasim MN Hammond Paula T PT
Advanced materials (Deerfield Beach, Fla.) 20120207 11
Osteophilic modular nanostructured multilayers containing hydroxyapatite nanoparticles complexed with a natural polymer chitosan create an osteoconductive surface for mesenchymal stem cells (MSCs). Coupled with the sustained release of physiological amounts of osteoinductive bone morphogenetic protein over several days from degradable poly(β-amino ester) based multilayers, this single coating results in a synergistic accelerated and upregulated differentiation of MSCs into osteoblasts laying dow ...[more]
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