Ontology highlight
ABSTRACT:
SUBMITTER: Lohcharoenkal W
PROVIDER: S-EPMC3875633 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Lohcharoenkal Warangkana W Wang Liying L Stueckle Todd A TA Dinu Cerasela Zoica CZ Castranova Vincent V Liu Yuxin Y Rojanasakul Yon Y
ACS nano 20130812 9
Malignant mesothelioma is one of the most aggressive forms of cancer known. Recent studies have shown that carbon nanotubes (CNTs) are biopersistent and induce mesothelioma in animals, but the underlying mechanisms are not known. Here, we investigate the effect of long-term exposure to high aspect ratio CNTs on the aggressive behaviors of human pleural mesothelial cells, the primary cellular target of human lung mesothelioma. We show that chronic exposure (4 months) to single- and multiwalled CN ...[more]