Ontology highlight
ABSTRACT:
SUBMITTER: Rousseau P
PROVIDER: S-EPMC390272 | biostudies-literature | 2004
REPOSITORIES: biostudies-literature
Rousseau Philippe P Gueguen Erwan E Duval-Valentin Guy G Chandler Mick M
Nucleic acids research 20040223 4
The transposase of IS911, a member of the IS3 family of bacterial insertion sequences, is composed of a catalytic domain located at its C-terminal end and a DNA binding domain located at its N-terminal end. Analysis of the transposases of over 60 members of the IS3 family revealed the presence of a helix-turn-helix (HTH) motif within the N-terminal region. Alignment of these potential secondary structures further revealed a completely conserved tryptophan residue similar to that found in the HTH ...[more]