Ontology highlight
ABSTRACT:
SUBMITTER: Lim KW
PROVIDER: S-EPMC3905899 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Nucleic acids research 20130902 22
Single-stranded DNA overhangs at the ends of human telomeric repeats are capable of adopting four-stranded G-quadruplex structures, which could serve as potential anticancer targets. Out of the five reported intramolecular human telomeric G-quadruplex structures, four were formed in the presence of K(+) ions and only one in the presence of Na(+) ions, leading often to a perception that this structural polymorphism occurs exclusively in the presence of K(+) but not Na(+). Here we present the stru ...[more]