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Fluorinated graphene oxide; a new multimodal material for biological applications.

ABSTRACT: Fluorinated graphene oxide (FGO) is reported for the first time as a magnetically responsive drug carrier that can serve both as a magnetic resonance imaging (MRI) and photoacoustic contrast agent, under preclinical settings, and as a type of photothermal therapy. Its hydrophilic nature facilitates biocompatibility. FGO as a broad wavelength absorber, with high charge transfer and strong non-linear scattering is optimal for NIR laser-induced hyperthermia.

SUBMITTER: Romero-Aburto R

PROVIDER: S-EPMC3938113 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature

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Fluorinated graphene oxide; a new multimodal material for biological applications.

Romero-Aburto Rebeca R Narayanan Tharangattu N TN Nagaoka Yutaka Y Hasumura Takashi T Mitcham Trevor M TM Fukuda Takahiro T Cox Paris J PJ Bouchard Richard R RR Maekawa Toru T Kumar D Sakthi DS Torti Suzy V SV Mani Sendurai A SA Ajayan Pulickel M PM

Advanced materials (Deerfield Beach, Fla.) 20130827 39

Fluorinated graphene oxide (FGO) is reported for the first time as a magnetically responsive drug carrier that can serve both as a magnetic resonance imaging (MRI) and photoacoustic contrast agent, under preclinical settings, and as a type of photothermal therapy. Its hydrophilic nature facilitates biocompatibility. FGO as a broad wavelength absorber, with high charge transfer and strong non-linear scattering is optimal for NIR laser-induced hyperthermia. ...[more]

PMID: 24038195

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