The genetic overlap between schizophrenia and height.
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ABSTRACT:
SUBMITTER: Bacanu SA
PROVIDER: S-EPMC3939673 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Publications
The genetic overlap between schizophrenia and height.
Bacanu Silviu-Alin SA Chen Xianging X Kendler Kenneth S KS
Schizophrenia research 20131112 1-3
Epidemiological studies suggest that height and schizophrenia risk are inversely correlated. These findings might arise because i) height and schizophrenia share genetic variants and ii) the effects of these shared variants are in opposite direction for the two traits. We use genome wide association data to empirically evaluate these hypotheses. We find that variants which impact on height and risk for schizophrenia are distributed across several genomic regions and the directions of effect vary ...[more]
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