Ontology highlight
ABSTRACT:
SUBMITTER: Chang YC
PROVIDER: S-EPMC3944459 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Chang Yi-Cheng YC Yu Yu-Hsiang YH Shew Jin-Yuh JY Lee Wei-Jei WJ Hwang Juey-Jen JJ Chen Yen-Hui YH Chen Yet-Ran YR Wei Pei-Chi PC Chuang Lee-Ming LM Lee Wen-Hwa WH
EMBO molecular medicine 20130704 8
Elevated oxidative stress is closely associated with obesity. Emerging evidence shows that instead of being a consequence of obesity, oxidative stress may also contribute to fat formation. Nonselenocysteine-containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) is a conserved oxidative stress sensor/transducer and deficiency of NPGPx causes accumulation of reactive oxygen species (ROS). In this communication, we show that NPGPx was highly expressed in preadipocytes of adipose tissu ...[more]