Ontology highlight
ABSTRACT:
SUBMITTER: Del Zompo M
PROVIDER: S-EPMC3960057 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Del Zompo Maria M Deleuze Jean-François JF Chillotti Caterina C Cousin Emmanuelle E Niehaus Dana D Ebstein Richard P RP Ardau Raffaella R Macé Sandrine S Warnich Louise L Mujahed Mustafa M Severino Giovanni G Dib Colette C Jordaan Esme E Murad Ibrahim I Soubigou Stéphane S Koen Liezl L Bannoura Issam I Rocher Corinne C Laurent Claudine C Derock Murielle M Faucon Biguet Nicole N Mallet Jacques J Meloni Rolando R
Molecular genetics & genomic medicine 20131212 2
GPR88, coding for a G protein-coupled orphan receptor that is highly represented in the striatum, is a strong functional candidate gene for neuropsychiatric disorders and is located at 1p22-p21, a chromosomal region that we have previously linked to bipolar disorder (BD) in the Sardinian population. In order to ascertain the relevance of GPR88 as a risk factor for psychiatric diseases, we performed a genetic association analysis between GPR88 and BD in a sample of triads (patient and both parent ...[more]