Ontology highlight
ABSTRACT:
SUBMITTER: Dickerman BK
PROVIDER: S-EPMC3962003 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Dickerman Benjamin K BK McDonald Jocelyn A JA Sen Ganes C GC
F1000Research 20131018
The dsRNA binding protein (dsRBP) PACT was first described as an activator of the dsRNA dependent protein kinase PKR in response to stress signals. Additionally, it has been identified as a component of the small RNA processing pathway. A role for PACT in this pathway represents an important interplay between two modes of post-transcriptional gene regulation. The function of PACT in this context is poorly understood. Thus, additional approaches are required to clarify the mechanism by which ...[more]