Unknown

Dataset Information

0

Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens.


ABSTRACT: Two new marine cyanobacterial natural products, parguerene (1) and precarriebowmide (2), were isolated from a collection of Moorea producens obtained from La Parguera, Puerto Rico. The planar structures of both were deduced by 2D NMR spectroscopy and mass spectrometry. Parguerene is a modified acyl amide with some structural similarity to the bacterial metabolite stipiamide (3), whereas precarriebowmide is a lipopeptide and represents a minor modification compared to two other known metabolites, carriebowmide (4) and carriebowmide sulfone (5). The identification of 2 led to an investigation into whether carriebowmide and carriebowmide sulfone were true secondary metabolites or isolation artifacts.

SUBMITTER: Mevers E 

PROVIDER: S-EPMC3962764 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens.

Mevers Emily E   Byrum Tara T   Gerwick William H WH  

Journal of natural products 20130917 9


Two new marine cyanobacterial natural products, parguerene (1) and precarriebowmide (2), were isolated from a collection of Moorea producens obtained from La Parguera, Puerto Rico. The planar structures of both were deduced by 2D NMR spectroscopy and mass spectrometry. Parguerene is a modified acyl amide with some structural similarity to the bacterial metabolite stipiamide (3), whereas precarriebowmide is a lipopeptide and represents a minor modification compared to two other known metabolites,  ...[more]

Similar Datasets

| S-EPMC5742827 | biostudies-literature
| S-EPMC4278201 | biostudies-literature
| S-EPMC6460272 | biostudies-literature
| S-EPMC7142784 | biostudies-literature
| S-EPMC4052313 | biostudies-literature
| S-EPMC7037229 | biostudies-literature
| S-EPMC4519256 | biostudies-literature
| S-EPMC6272925 | biostudies-literature
| S-EPMC5748289 | biostudies-literature
| S-EPMC5006271 | biostudies-literature