Ontology highlight
ABSTRACT:
SUBMITTER: Ma S
PROVIDER: S-EPMC3967148 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Ma Sanyuan S Chang Jiasong J Wang Xiaogang X Liu Yuanyuan Y Zhang Jianduo J Lu Wei W Gao Jie J Shi Run R Zhao Ping P Xia Qingyou Q
Scientific reports 20140327
CRISPR/Cas9, a bacterial adaptive immune system derived genome-editing technique, has become to be one of the most compelling topics in biotechnology. Bombyx mori is an economically important insect and a model organism for studying lepidopteran and arthropod biology. Here we reported highly efficient and multiplex genome editing in B. mori cell line and heritable site-directed mutagenesis of Bmku70, which is required for NHEJ pathway and also related to antigen diversity, telomere length mainte ...[more]