Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC3975380 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Liu Hongzhe H Huang Xiangwang X Liu Xiangyang X Xiao Sheng S Zhang Yi Y Xiang Tiecheng T Shen Xiongjie X Wang Guoping G Sheng Bin B
International journal of molecular sciences 20140305 3
The precise role of nucleus pulposus cell proliferation in the pathogenesis of intervertebral disc degeneration remains to be elucidated. Recent findings have revealed that microRNAs, a class of small noncoding RNAs, may regulate cell proliferation in many pathological conditions. Here, we showed that miR-21 was significantly upregulated in degenerative nucleus pulposus tissues when compared with nucleus pulposus tissues that were isolated from patients with idiopathic scoliosis and that miR-10b ...[more]