Ontology highlight
ABSTRACT:
SUBMITTER: Ravandi F
PROVIDER: S-EPMC3976223 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Ravandi Farhad F Jorgensen Jeffrey L JL Thomas Deborah A DA O'Brien Susan S Garris Rebecca R Faderl Stefan S Huang Xuelin X Wen Sijin S Burger Jan A JA Ferrajoli Alessandra A Kebriaei Partow P Champlin Richard E RE Estrov Zeev Z Challagundla Pramoda P Wang Sa A SA Luthra Rajyalakshmi R Cortes Jorge E JE Kantarjian Hagop M HM
Blood 20130708 7
From 2001 to 2011, 122 patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia were treated with chemotherapy + imatinib (n = 54) or + dasatinib (n = 68). One hundred fifteen (94%) achieved complete remission (CR) including 101 patients who achieved it with only 1 induction course and had at least 1 minimal residual disease (MRD) assessment; 25 patients underwent an allogeneic stem cell transplant in first CR and were excluded, leaving 76 patients as the subje ...[more]