Ontology highlight
ABSTRACT:
SUBMITTER: Hall MH
PROVIDER: S-EPMC3984007 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Hall Mei-Hua MH Levy Deborah L DL Salisbury Dean F DF Haddad Steve S Gallagher Patience P Lohan Mary M Cohen Bruce B Ongür Dost D Smoller Jordan W JW
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20131108 1
Genome-wide association studies (GWAS) have identified multiple single nucleotide polymorphisms (SNPs) as disease associated variants for schizophrenia (SCZ), bipolar disorder (BPD), or both. Although these results are statistically robust, the functional effects of these variants and their role in the pathophysiology of SCZ or BPD remain unclear. Dissecting the effects of risk genes on distinct domains of brain function can provide important biological insights into the mechanisms by which thes ...[more]