Ontology highlight
ABSTRACT:
SUBMITTER: Ghoshal S
PROVIDER: S-EPMC6276175 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Malaria journal 20181203 1
<h4>Background</h4>Despite its immunogenicity, the polymorphic nature of merozoite surface protein 1, an important vaccine candidate for Plasmodium falciparum malaria, remains a concern. This study analyses the impact of genetic variability and parasite population structure on epitope organization of different MSP1 segments.<h4>Methods</h4>Altogether 98 blood samples collected from P. falciparum infected mild and severe malaria patients of Chhattisgarh and West Bengal were used to sequence regio ...[more]