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5-Chloro-5''-(4-chloro-benzyl-idene)-4'-(4-chloro-phen-yl)-1',1''-dimethyldi-spiro-[indoline-3,2'-pyrrolidine-3',3''-piperidine]-2,4''-dione.

ABSTRACT: The racemic title compound, C30H26Cl3N3O2, comprises two spiro links, the first connecting the piperidine and pyrrolidine rings and the other connecting the indole and pyrrolidine rings. The piperidine ring adopts a half-chair conformation, while the pyrrolidine ring has an envelope conformation with the unsubstituted C atom as the flap. The dihedral angles between the two p-Cl-substituted benzene rings and the indole ring are 33.13?(14) and 54.11?(14)°. In the crystal, mol-ecules form inversion dimers through pairs of N-H?O hydrogen bonds [graph set R 2 (2)(8)]. Aromatic C-H?O hydrogen bonds extend these dimers into a ribbon structure, enclosing R (2) 2(14) ring motifs, along the a-axis direction.

SUBMITTER: Farag IS

PROVIDER: S-EPMC3998502 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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5-Chloro-5''-(4-chloro-benzyl-idene)-4'-(4-chloro-phen-yl)-1',1''-dimethyldi-spiro-[indoline-3,2'-pyrrolidine-3',3''-piperidine]-2,4''-dione.

Farag I S Ahmed IS Girgis Adel S AS Ramadan A A AA Moustafa A M AM Moustafa A M AM Mabied Ahmed F AF

Acta crystallographica. Section E, Structure reports online 20140228 Pt 3

The racemic title compound, C30H26Cl3N3O2, comprises two spiro links, the first connecting the piperidine and pyrrolidine rings and the other connecting the indole and pyrrolidine rings. The piperidine ring adopts a half-chair conformation, while the pyrrolidine ring has an envelope conformation with the unsubstituted C atom as the flap. The dihedral angles between the two p-Cl-substituted benzene rings and the indole ring are 33.13 (14) and 54.11 (14)°. In the crystal, mol-ecules form inversion ...[more]

PMID: 24765059

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