Ontology highlight
ABSTRACT:
SUBMITTER: Chuprakov S
PROVIDER: S-EPMC3999524 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20131217 1
Rhodium(II) azavinyl carbenes, conveniently generated from 1-sulfonyl-1,2,3-triazoles, undergo a facile, mild, and convergent formal 1,3-insertion into N-H and O-H bonds of primary and secondary amides, various alcohols, and carboxylic acids to afford a wide range of vicinally bisfunctionalized (Z)-olefins with perfect regio- and stereoselectivity. Utilizing the distinctive functionality installed through these reactions, a number of subsequent rearrangements and cyclizations expand the repertoi ...[more]