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Harnessing the ?-Silicon Effect for Regioselective and Stereoselective Rhodium(II)-Catalyzed C-H Functionalization by Donor/Acceptor Carbenes Derived from 1-Sulfonyl-1,2,3-triazoles.

ABSTRACT: The regioselective and enantioselective intermolecular sp3 C-H functionalization of silicon-substituted alkanes was accomplished using Rh2( S-NTTL)4 with readily available 1-sulfonyl-1,2,3-triazoles as carbene precursors. These reactions generate a diverse array of stereodefined substituted silaalkanes.

SUBMITTER: Garlets ZJ

PROVIDER: S-EPMC6035867 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Harnessing the β-Silicon Effect for Regioselective and Stereoselective Rhodium(II)-Catalyzed C-H Functionalization by Donor/Acceptor Carbenes Derived from 1-Sulfonyl-1,2,3-triazoles.

Garlets Zachary J ZJ Davies Huw M L HML

Organic letters 20180411 8

The regioselective and enantioselective intermolecular sp3 C-H functionalization of silicon-substituted alkanes was accomplished using Rh2( S-NTTL)4 with readily available 1-sulfonyl-1,2,3-triazoles as carbene precursors. These reactions generate a diverse array of stereodefined substituted silaalkanes. ...[more]

PMID: 29638130

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