Ontology highlight
ABSTRACT:
SUBMITTER: Allen LJ
PROVIDER: S-EPMC4004272 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20140404 15
This paper reports a room temperature visible light photocatalyzed method for the C-H amination of arenes and heteroarenes. A key enabling advance in this work is the design of N-acyloxyphthalimides as precursors to nitrogen-based radical intermediates for these transformations. A broad substrate scope is presented, including the selective meta-amination of pyridine derivatives. A radical aromatic substitution mechanism is proposed. ...[more]