Ontology highlight
ABSTRACT:
SUBMITTER: Chang YM
PROVIDER: S-EPMC4005659 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Chang Yu-Ming YM Ho Chun-Han CH Chen Cammy K-M CK Maestre-Reyna Manuel M Chang-Chien Masatoshi Weiting MW Wang Andrew H-J AH
Nucleic acids research 20140214 8
The teicoplanin-associated locus regulator (TcaR) regulates gene expression of proteins on the intercellular adhesion (ica) locus involved in staphylococci poly-N-acetylglucosamine biosynthesis. The absence of TcaR increases poly-N-acetylglucosamine production and promotes biofilm formation. Until recently, the mechanism of multiple antibiotic resistance regulator family protein members, such as TcaR, was restricted to binding double-stranded DNA. However, we recently found that TcaR strongly in ...[more]