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Ultrasound-triggered regulation of blood glucose levels using injectable nano-network.

ABSTRACT: The integration of an injectable insulin-encapsulated nano-network with a focused ultrasound system (FUS) can remotely regulate insulin release both in vitro and in vivo. A single subcutaneous injection of the nano-network with intermittent FUS administration facilitates reduction of the blood glucose levels in type 1 diabetic mice for up to 10 d.

SUBMITTER: Di J

PROVIDER: S-EPMC4026341 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature

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Ultrasound-triggered regulation of blood glucose levels using injectable nano-network.

Di Jin J Price Jennifer J Gu Xiao X Jiang Xiaoning X Jing Yun Y Gu Zhen Z

Advanced healthcare materials 20131119 6

The integration of an injectable insulin-encapsulated nano-network with a focused ultrasound system (FUS) can remotely regulate insulin release both in vitro and in vivo. A single subcutaneous injection of the nano-network with intermittent FUS administration facilitates reduction of the blood glucose levels in type 1 diabetic mice for up to 10 d. ...[more]

PMID: 24255016

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