Ontology highlight
ABSTRACT:
SUBMITTER: Boada M
PROVIDER: S-EPMC4031637 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Boada M M Antúnez C C Ramírez-Lorca R R DeStefano A L AL González-Pérez A A Gayán J J López-Arrieta J J Ikram M A MA Hernández I I Marín J J Galán J J JJ Bis J C JC Mauleón A A Rosende-Roca M M Moreno-Rey C C Gudnasson V V Morón F J FJ Velasco J J Carrasco J M JM Alegret M M Espinosa A A Vinyes G G Lafuente A A Vargas L L Fitzpatrick A L AL Launer L J LJ Sáez M E ME Vázquez E E Becker J T JT López O L OL Serrano-Ríos M M Tárraga L L van Duijn C M CM Real L M LM Seshadri S S Ruiz A A
Molecular psychiatry 20130716 6
To identify loci associated with Alzheimer disease, we conducted a three-stage analysis using existing genome-wide association studies (GWAS) and genotyping in a new sample. In Stage I, all suggestive single-nucleotide polymorphisms (at P<0.001) in a previously reported GWAS of seven independent studies (8082 Alzheimer's disease (AD) cases; 12 040 controls) were selected, and in Stage II these were examined in an in silico analysis within the Cohorts for Heart and Aging Research in Genomic Epide ...[more]