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Full-genome sequence of human betacoronavirus 2c jordan-n3/2012 after serial passage in Mammalian cells.

ABSTRACT: Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus.

SUBMITTER: Frey KG 

PROVIDER: S-EPMC4038873 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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Full-genome sequence of human betacoronavirus 2c jordan-n3/2012 after serial passage in Mammalian cells.

Frey Kenneth G KG   Redden Cassie L CL   Bishop-Lilly Kimberly A KA   Johnson Reed R   Hensley Lisa E LE   Raviprakash Kanakatte K   Luke Thomas T   Kochel Tad T   Mokashi Vishwesh P VP   Defang Gabriel N GN  

Genome announcements 20140529 3

Middle East respiratory syndrome coronavirus (MERS-CoV) is the etiologic agent of a highly lethal pneumonia. Here, we report the full-genome sequence of the Jordan-N3/2012 strain after serial passage in two distinct mammalian cell lines. The genome exhibits noteworthy stability, which may inform the development of vaccines and therapeutics used to treat infection with this virus. ...[more]

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