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Scalable manufacture of built-to-order nanomedicine: spray-assisted layer-by-layer functionalization of PRINT nanoparticles.

ABSTRACT: Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery.

SUBMITTER: Morton SW

PROVIDER: S-EPMC4040353 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Scalable manufacture of built-to-order nanomedicine: spray-assisted layer-by-layer functionalization of PRINT nanoparticles.

Morton Stephen W SW Herlihy Kevin P KP Shopsowitz Kevin E KE Deng Zhou J ZJ Chu Kevin S KS Bowerman Charles J CJ Desimone Joseph M JM Hammond Paula T PT

Advanced materials (Deerfield Beach, Fla.) 20130701 34

Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery. ...[more]

PMID: 23813892

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