Ontology highlight
ABSTRACT:
SUBMITTER: Gao H
PROVIDER: S-EPMC4046710 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Gao Haijun H Yallampalli Uma U Yallampalli Chandra C
Frontiers in bioscience (Elite edition) 20130101 2
Whether and how gestational protein restriction (PR) affects placental development and function remain unknown. To test the hypothesis that PR can affect trophoblast differentiation in mid-and late pregnancy, rats were fed a 20% or an isocaloric 6% protein diet from Day 1 to 14 or 18 of pregnancy and effects of PR on trophoblast differentiation were determined by changes in expressions of marker gene(s) for trophoblast lineages. At Day 18 of pregnancy, PR increased expressions of Esrrb, Id1 andI ...[more]