Ontology highlight
ABSTRACT:
SUBMITTER: Fiaturi N
PROVIDER: S-EPMC4063996 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Fiaturi Najla N Castellot John J JJ Nielsen Heber C HC
Journal of cell communication and signaling 20140531 2
Lung immaturity is the major cause of morbidity and mortality in premature infants, especially those born <28 weeks gestation. Proper lung development from 23-28 weeks requires coordinated cell proliferation and differentiation. Infants born at this age are at high risk for respiratory distress syndrome (RDS), a lung disease characterized by insufficient surfactant production due to immaturity of the alveoli and its constituent cells in the lung. The ErbB4 receptor and its stimulation by neuregu ...[more]