Ontology highlight
ABSTRACT:
SUBMITTER: Booth AJR
PROVIDER: S-EPMC4064686 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Booth Alexander J R AJR Blanchard Guy B GB Adams Richard J RJ Röper Katja K
Developmental cell 20140601 5
The cytoskeleton is a major determinant of cell-shape changes that drive the formation of complex tissues during development. Important roles for actomyosin during tissue morphogenesis have been identified, but the role of the microtubule cytoskeleton is less clear. Here, we show that during tubulogenesis of the salivary glands in the fly embryo, the microtubule cytoskeleton undergoes major rearrangements, including a 90° change in alignment relative to the apicobasal axis, loss of centrosomal a ...[more]