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Flavanones from Miconia prasina.

ABSTRACT: A glycosidic flavanone miconioside C (1) has been isolated from the methanolic extract of the stems of Miconia prasina, together with 7-O-?-D-apiofuranosyl-(1?6)-?-D-glucopyranosylmatteucinol (2), miconioside B (3), matteucinol (4), farrerol (5) and desmethoxymatteucinol (6). Their structures were mainly established by extensive NMR studies (1H NMR, 13C NMR, DEPT, 1H-1H COSY, HSQC, HMBC) and mass spectrometry. The compounds 1- 3 were evaluated for in vitro binding assays using cannabinoid receptors (CB1 and CB2).

SUBMITTER: Tarawneh AH

PROVIDER: S-EPMC4070512 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Flavanones from Miconia prasina.

Tarawneh Amer H AH León Francisco F Ibrahim Mohammed A MA Pettaway Sara S McCurdy Christopher R CR Cutler Stephen J SJ

Phytochemistry letters 20140201

A glycosidic flavanone miconioside C (1) has been isolated from the methanolic extract of the stems of Miconia prasina, together with 7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranosylmatteucinol (2), miconioside B (3), matteucinol (4), farrerol (5) and desmethoxymatteucinol (6). Their structures were mainly established by extensive NMR studies (1H NMR, 13C NMR, DEPT, 1H-1H COSY, HSQC, HMBC) and mass ...[more]

PMID: 24976876

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