Ontology highlight
ABSTRACT:
SUBMITTER: Jiang K
PROVIDER: S-EPMC4071053 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Jiang Kailun K Cao Sijia S Cui Jing Z JZ Matsubara Joanne A JA
Journal of clinical & experimental ophthalmology 20130201
Age-related macular degeneration (AMD) is a neurodegenerative disease characterized by retinal cell atrophy, and/or choroidal neovascularization in the macula and constitutes the most common cause of blindness among the elderly in industrialized countries. The management of AMD is constrained by our insufficient knowledge of its underlying mechanisms. Recent studies point towards an emerging involvement of interferon-gamma (IFN-γ), a soluble cytokine associated with innate and adaptive immunity. ...[more]