Optimizing the selective recognition of protein isoforms through tuning of nanoparticle hydrophobicity.
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ABSTRACT:
SUBMITTER: Chen K
PROVIDER: S-EPMC4073475 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Optimizing the selective recognition of protein isoforms through tuning of nanoparticle hydrophobicity.
Chen Kaimin K Rana Subinoy S Moyano Daniel F DF Xu Yisheng Y Guo Xuhong X Rotello Vincent M VM
Nanoscale 20140601 12
We demonstrate that ligand hydrophobicity can be used to increase affinity and selectivity of binding between monolayer-protected cationic gold nanoparticles and β-lactoglobulin protein isoforms containing two amino acid mutations. ...[more]
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