Ontology highlight
ABSTRACT:
SUBMITTER: Mannino M
PROVIDER: S-EPMC4085484 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Mannino Mariella M Gomez-Roman Natividad N Hochegger Helfrid H Chalmers Anthony J AJ
Stem cell research 20140511 1
Glioma stem-cell-like cells are considered to be responsible for treatment resistance and tumour recurrence following chemo-radiation in glioblastoma patients, but specific targets by which to kill the cancer stem cell population remain elusive. A characteristic feature of stem cells is their ability to undergo both symmetric and asymmetric cell divisions. In this study we have analysed specific features of glioma stem cell mitosis. We found that glioma stem cells appear to be highly prone to un ...[more]