The cryptic sexual strategies of human fungal pathogens.
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ABSTRACT:
SUBMITTER: Ene IV
PROVIDER: S-EPMC4102497 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
The cryptic sexual strategies of human fungal pathogens.
Ene Iuliana V IV Bennett Richard J RJ
Nature reviews. Microbiology 20140401 4
Sexual reproduction is a pervasive attribute of eukaryotic species and is now recognized to occur in many clinically important human fungal pathogens. These fungi use sexual or parasexual strategies for various purposes that can have an impact on pathogenesis, such as the formation of drug-resistant isolates, the generation of strains with increased virulence or the modulation of interactions with host cells. In this Review, we examine the mechanisms regulating fungal sex and the consequences of ...[more]
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