An evolutionary perspective on zinc uptake by human fungal pathogens.
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ABSTRACT:
SUBMITTER: Wilson D
PROVIDER: S-EPMC4433550 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
An evolutionary perspective on zinc uptake by human fungal pathogens.
Metallomics : integrated biometal science 20150601 6
The mammalian immune system has evolved sophisticated mechanisms to withhold essential micronutrients from invading pathogens. These processes, collectively known as nutritional immunity serve to limit microbial proliferation and bolster killing of the invader. Successful pathogens, therefore, have developed strategies to counteract nutritional immunity and acquire essential micronutrients in the restrictive environment of the infected host. Here I take advantage of the now large number of seque ...[more]
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