Ontology highlight
ABSTRACT:
SUBMITTER: Gujarathi S
PROVIDER: S-EPMC4104368 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Tetrahedron 20140801 34
Development of an efficient synthesis of fully substituted pyrroles via a sequential as a catalyst. The propargylation/amination/cycloisomerization was accomplished using AgSbF<sub>6</sub> one-pot three-component reaction of propargylic alcohols, 1,3-dicarbonyl compounds, and primary amines proceeds at a mild temperature, which prevents the formation of furan by-product. The reaction was also successfully applied to the more basic aliphatic amines with the addition of 1.1 eq. of acetic acid. ...[more]