Ontology highlight
ABSTRACT:
SUBMITTER: Hong CS
PROVIDER: S-EPMC4107115 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Hong Chang-Soo CS Devotta Arun A Lee Young-Hoon YH Park Byung-Yong BY Saint-Jeannet Jean-Pierre JP
Developmental neurobiology 20140305 9
Transcription factors Pax3 and Zic1 are two important regulators of cell fate decision at the neural plate border, where they act synergistically to promote neural crest (NC) formation. To understand the role of these factors in NC development, we performed a microarray analysis to identify downstream targets of Pax3 and Zic1 in Xenopus embryos. Among the genes identified was a member of transcription factor activator protein 2 (Tfap2) family, Tfap2 epsilon (Tfap2e). Tfap2e is first expressed at ...[more]