Ontology highlight
ABSTRACT:
SUBMITTER: Prasad MS
PROVIDER: S-EPMC7050198 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Prasad Maneeshi S MS Uribe-Querol Eileen E Marquez Jonathan J Vadasz Stephanie S Yardley Nathan N Shelar Patrick B PB Charney Rebekah M RM García-Castro Martín I MI
Developmental biology 20191011 1
Cell fate specification defines the earliest steps towards a distinct cell lineage. Neural crest, a multipotent stem cell population, is thought to be specified from the ectoderm, but its varied contributions defy canons of segregation potential and challenges its embryonic origin. Aiming to resolve this conflict, we have assayed the earliest specification of neural crest using blastula stage chick embryos. Specification assays on isolated chick epiblast explants identify an intermediate region ...[more]