Ontology highlight
ABSTRACT:
SUBMITTER: Kim Y
PROVIDER: S-EPMC4113818 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Kim Youngju Y Ogura Hiromu H Akasaka Kazuaki K Oikawa Tsutomu T Matsuura Nobuyasu N Imada Chiaki C Yasuda Hisato H Igarashi Yasuhiro Y
Marine drugs 20140708 7
One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2-4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment. Structures of these compounds were determined on the basis of spectroscopic data including NMR and MS. γ-Pyrones 2-4 were found to induce adiponectin production in murine ST-13 preadipocyte cells but the α-pyrone 1 had no activity. The absolute configuration of the anteiso-methyl branching in 4 was determined ...[more]