Ontology highlight
ABSTRACT:
SUBMITTER: Tsilidis KK
PROVIDER: S-EPMC4119174 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Tsilidis Konstantinos K KK Helzlsouer Kathy J KJ Smith Michael W MW Grinberg Victoriya V Hoffman-Bolton Judith J Clipp Sandra L SL Visvanathan Kala K Platz Elizabeth A EA
Cancer causes & control : CCC 20091101 9
<h4>Objective and methods</h4>The association of 17 candidate single nucleotide polymorphisms (SNPs) in IL10 and other immune response genes (CRP, TLR4, IL6, IL1B, IL8, TNF, RNASEL) and genes related to obesity (PPARG, TCF7L2, ADIPOQ, LEP) with colorectal cancer was investigated. Haplotype tagging SNPs were chosen for IL10, CRP, and TLR4. Incident colorectal cancer cases (n = 208) and matched controls (n = 381) were identified between baseline in 1989 and 2003 among participants in the CLUE II c ...[more]