Ontology highlight
ABSTRACT:
SUBMITTER: Smith AT
PROVIDER: S-EPMC4119550 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Smith Aaron T AT Smith Kyle P KP Rosenzweig Amy C AC
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20140413 6
The P1B-ATPases are integral membrane proteins that couple ATP hydrolysis to metal cation transport. Widely distributed across all domains of life, these enzymes have been previously shown to transport copper, zinc, cobalt, and other thiophilic heavy metals. Recent data suggest that these enzymes may also be involved in nickel and/or iron transport. Here we have exploited large amounts of genomic data to examine and classify the various P1B-ATPase subfamilies. Specifically, we have combined new ...[more]