Ontology highlight
ABSTRACT:
SUBMITTER: Hunter MS
PROVIDER: S-EPMC4129423 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Scientific reports 20140812
We present results from experiments at the Linac Coherent Light Source (LCLS) demonstrating that serial femtosecond crystallography (SFX) can be performed to high resolution (~2.5 Å) using protein microcrystals deposited on an ultra-thin silicon nitride membrane and embedded in a preservation medium at room temperature. Data can be acquired at a high acquisition rate using x-ray free electron laser sources to overcome radiation damage, while sample consumption is dramatically reduced compared to ...[more]